• 11/12/2021
• 
• Aviva Stadium  D04 K5F9
• Leinster
• 
• 
• 15:15
• Leinster
• 15:15
• Bath
• Bath
• More +
• More +
Venue: Aviva Stadium

• 17/12/2021
• 
• Kingspan Stadium  BT6 0FT
• Ulster
• 
• 
• 20:00
• Ulster
• 20:00
• Northampton
• Northampton
• More +
• More +
Venue: Kingspan Stadium

• 18/12/2021
• 
• AJ Bell Stadium  M30 7EY
• Sale Sharks
• 15:15
• Sale Sharks
• 15:15
• Clermont
• Clermont
• More +
• More +
Referee: Frank Murphy
Venue: AJ Bell Stadium

• 15/01/2022
• 
• Dexcom Stadium  H91 H340
• Connacht
• 15:15
• Connacht
• 15:15
• Leicester Tigers
• Leicester Tigers
• More +
• More +
Venue: Dexcom Stadium

• 16/01/2022
• 
• RDS Arena  D04 PD93
• Leinster
• 
• 
• 13:00
• Leinster
• 13:00
• Montpellier
• Montpellier
• More +
• More +
Venue: RDS Arena

• 16/01/2022
• 
• Stade Marcel-Michelin  63100
• Clermont
• 18:30
• Clermont
• 18:30
• Sale Sharks
• Sale Sharks
• More +
• More +
Referee: Frank Murphy
Venue: Stade Marcel-Michelin

• 22/01/2022
• 
• Kingspan Stadium  BT6 0FT
• Ulster
• 
• 
• 17:30
• Ulster
• 17:30
• Clermont
• Clermont
• More +
• More +
Referee: Luke Pearce RFU (Pending)
Venue: Kingspan Stadium

• 23/01/2022
• 
• Paris La Défense Arena  92000
• Racing 92
• 16:15
• Racing 92
• 16:15
• Northampton
• Northampton
• More +
• More +
Venue: Paris La Défense Arena

• 23/01/2022
• 
• GGL Stadium  34070
• Montpellier
• 18:30
• Montpellier
• 18:30
• Exeter Chiefs
• Exeter Chiefs
• More +
• More +
Referee: Frank Murphy
Venue: GGL Stadium

• 15/04/2022
• 
• Aviva Stadium  D04 K5F9
• Leinster
• 
• 
• 17:30
• Leinster
• 17:30
• Connacht
• Connacht
• More +
• More +
Venue: Aviva Stadium

• 16/04/2022
• 
• Kingspan Stadium  BT6 0FT
• Ulster
• 
• 
• 20:00
• Ulster
• 20:00
• Stade Toulousain
• Stade Toulousain
• More +
• More +
Venue: Kingspan Stadium

• 16/04/2022 17:30
• 17:30
• Leicester Tigers
• 27-3 v 17-2
• Leicester Tigers
• 27-3 v 17-2
• Clermont
• Clermont
• More +
• More +
Referee: Andrew Brace
Venue: Welford Road
Venue: Welford Road

• 16/04/2022 15:00
• 15:00
• Munster
• 26- v 10-
• Munster
• 26- v 10-
• Exeter Chiefs
• Exeter Chiefs
• More +
• More +
Venue: Thomond Park
Venue: Thomond Park

• 15/04/2022 20:00
• 20:00
• Bristol
• 0- v 0-
• Bristol
• 0- v 0-
• Sale Sharks
• Sale Sharks
• More +
• More +
Referee: Frank Murphy
Venue: Ashton Gate
Venue: Ashton Gate

• 10/04/2022 16:15
• 16:15
• Clermont
• 0- v 0-
• Clermont
• 0- v 0-
• Leicester Tigers
• Leicester Tigers
• More +
• More +
Venue: Stade Marcel-Michelin
Venue: Stade Marcel-Michelin

• 10/04/2022 14:00
• 14:00
• Montpellier
• 1-2 v 1-2
• Montpellier
• 1-2 v 1-2
• Harlequins
• Harlequins
• More +
• More +
Referee: Andrew Brace
Venue: GGL Stadium
Venue: GGL Stadium

• 08/04/2022 20:00
• 20:00
• Connacht
• 
• 0-0 v 0-0
• Connacht
• 0-0 v 0-0
• 
• Leinster
• Leinster
• More +
• More +
Venue: Dexcom Stadium
Venue: Dexcom Stadium

• 23/01/2022 15:15
• 15:15
• Munster
• 45-6 v 7-1
• Munster
• 45-6 v 7-1
• Wasps
• Wasps
• More +
• More +
Referee: Tual Trainini FFR (Pending)
Venue: Thomond Park
Venue: Thomond Park

• 22/01/2022 15:15
• 15:15
• Leicester Tigers
• 28-4 v 0-
• Leicester Tigers
• 28-4 v 0-
• Bordeaux
• Bordeaux
• More +
• More +
Referee: Andrew Brace
Venue: Welford Road
Venue: Welford Road

• 21/01/2022 20:00
• 20:00
• Harlequins
• 0-0 v 0-
• Harlequins
• 0-0 v 0-
• Castres
• Castres
• More +
• More +
Venue: The Stoop-Twickenham
Venue: The Stoop-Twickenham

• 15/01/2022 20:00
• 20:00
• Bristol
• 28-3 v 17-2
• Bristol
• 28-3 v 17-2
• Stade Francais
• Stade Francais
• More +
• More +
Referee: Andrew Brace
Venue: Ashton Gate
Venue: Ashton Gate

• 15/01/2022 13:00
• 13:00
• Wasps
• 0- v 0-
• Wasps
• 0- v 0-
• Stade Toulousain
• Stade Toulousain
• More +
• More +
Referee: Chris Busby
Venue: Ricoh Arena
Venue: Ricoh Arena

• 19/12/2021 18:30
• 18:30
• Stade Francais
• 0- v 0-
• Stade Francais
• 0- v 0-
• Bristol
• Bristol
• More +
• More +
Referee: Andrew Brace
Venue: Stade Jean Bouin
Venue: Stade Jean Bouin

• 12/12/2021 13:00
• 13:00
• Connacht
• 36-6 v 9-0
• Connacht
• 36-6 v 9-0
• Stade Francais
• Stade Francais
• More +
• More +
Referee: Luke Pearce RFU (Pending)
Venue: Dexcom Stadium
Venue: Dexcom Stadium

• 11/12/2021 16:15
• 16:15
• Bordeaux
• 0- v 0-
• Bordeaux
• 0- v 0-
• Leicester Tigers
• Leicester Tigers
• More +
• More +
Referee: Andrew Brace
Venue: Stade Chaban-Delmas
Venue: Stade Chaban-Delmas